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Effect of compressional forces on piroxicam polymorphs.

作者信息

Ghan G A, Lalla J K

机构信息

K. M. Kundnani College of Pharmacy, Plot No. 47, Worli, Bombay, India.

出版信息

J Pharm Pharmacol. 1992 Aug;44(8):678-81. doi: 10.1111/j.2042-7158.1992.tb05494.x.

Abstract

The effect of compressional force on the polymorphic transition in piroxicam has been examined, using pure polymorph, by differential scanning calorimetry, powder X-ray diffractometry and by determination of dissolution rates from tablets of the individual polymorphs. The needle shaped polymorph was found to undergo transition to the cubic polymorph during compression.

摘要

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