通过增加哺乳频率在闭经结束后抑制卵巢活动的可行性。

The feasibility of suppressing ovarian activity following the end of amenorrhoea by increasing the frequency of suckling.

作者信息

Gellén J J

机构信息

WHO Collaborating Centre for Research in Human Reproduction, Department of Obstetrics and Gynecology, Albert Szent-Györgyi Medical University, Szeged, Hungary.

出版信息

Int J Gynaecol Obstet. 1992 Dec;39(4):321-5. doi: 10.1016/0020-7292(92)90264-j.

DOI:10.1016/0020-7292(92)90264-j

PMID:1361466

Abstract

OBJECTIVE

To determine the feasibility of suppressing ovarian activity by increasing the frequency of suckling episodes.

METHOD

Prospective study was carried out with 19 exclusively breastfeeding volunteers. Ten subjects (experimental group) increased the suckling episodes by minimum 50% per day from the beginning of the first postpartum menses. Nine controls continued breastfeeding as before. Estradiol, progesterone, LH, FSH and prolactin were measured in blood samples, drawn twice a week up to the second postpartum menses or for 60 days, by RIA. Student's t-test was employed.

RESULT

The higher suckling frequency prevented ovulation in 7 of 10 cases examined according to the plasma progesterone concentration (< 9.5 nmol/l). Significantly higher average prolactin value could also be found in the experimental group (1038 (527) munits/l vs. 518 (245) munits/l; P < 0.05).

CONCLUSION

Results suggest that an earlier initiation of the increase in breastfeeding frequency may delay the resumption of ovulation. Frequent, full time lactation may reduce the risk of pregnancy.

摘要

目的

通过增加哺乳次数来确定抑制卵巢活动的可行性。

方法

对19名纯母乳喂养的志愿者进行前瞻性研究。10名受试者（实验组）自产后第一次月经开始，每天将哺乳次数至少增加50%。9名对照组受试者继续按以前的方式母乳喂养。通过放射免疫分析法（RIA）对血样中的雌二醇、孕酮、促黄体生成素（LH）、促卵泡生成素（FSH）和催乳素进行检测，每周采集两次血样，直至产后第二次月经或持续60天。采用学生t检验。