Martin Sophie G, Chang Fred
Department of Microbiology, Columbia University College of Physicians and Surgeons, 701 W. 168th Street, New York, NY 10032, USA.
Curr Biol. 2003 Sep 16;13(18):R711-3. doi: 10.1016/j.cub.2003.08.046.
Microtubules play a central role in the establishment of cell polarity by directing the transport of polarity determinants to their site of action. Recent work has revealed a novel membrane-anchoring mechanism which complements the microtubule transport of the fission yeast polarity determinant tea1p to ensure its retention at the cell tip.
微管在细胞极性确立过程中发挥核心作用,它将极性决定因子运输到其作用位点。最近的研究揭示了一种新的膜锚定机制,该机制补充了裂殖酵母极性决定因子tea1p的微管运输,以确保其保留在细胞顶端。