Robinson M K, Stephens P E
Inflammation Biology Group, Celltech Research Ltd, Slough, Berkshire, UK.
Curr Opin Biotechnol. 1992 Dec;3(6):662-7. doi: 10.1016/0958-1669(92)90013-9.
It has become increasingly clear over the last 20 years that the potential exists to modulate inflammatory responses with compounds that interfere with intercellular adhesion. This review highlights the adhesion interactions that occur during neutrophil extravasation and indicates some of the possible ways of disrupting these interactions.
在过去20年里越来越清楚的是,存在用干扰细胞间黏附的化合物来调节炎症反应的潜力。这篇综述强调了中性粒细胞渗出过程中发生的黏附相互作用,并指出了一些破坏这些相互作用的可能方式。