通过去除污染的粘多糖来纯化癌胚抗原。
Purification of carcinoembryonic antigen by removal of contaminating mucopolysaccharides.
作者信息
Pritchard D G, Todd C W
出版信息
Cancer Res. 1976 Dec;36(12):4699-701.
PMID:137073
Abstract
The fraction of carcinoembryonic antigen preparations not bound by concanavalin A was studied. A significant portion of this nonbound fraction of low antigenic activity was shown to be mucopolysaccharides by gas chromatography-mass spectrometry, cellulose acetate strip electrophoresis, and depolymerization by bovine testicular hyaluronidase.
摘要
研究了癌胚抗原制剂中未与伴刀豆球蛋白A结合的部分。通过气相色谱-质谱分析、醋酸纤维素纸条电泳以及牛睾丸透明质酸酶解聚，结果表明该低抗原活性的未结合部分中有很大一部分是粘多糖。
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