无菌、曾经无菌及普通大鼠体内的胆红素和尿胆素
Bilirubin and urobilins in germfree, ex-germfree, and conventional rats.
作者信息
GUSTAFSSON B E, LANKE L S
出版信息
J Exp Med. 1960 Dec 1;112(6):975-81. doi: 10.1084/jem.112.6.975.
Abstract
No urobilinogens are present in the feces or urine of germfree rats. After contamination of germfree animals with feces from conventional animals the exgermfree rats produced urobilins to the same extent as conventional animals on the same diet. The negative urobilin test turned positive in germfree animals infected with a single Clostridium-like microorganism isolated from the intestinal contents of rats with urobilins in the feces. The output increased in these monoinfected animals after superinfection with a strain of E. coli but never reached the values of conventional animals.
摘要
无菌大鼠的粪便或尿液中不存在尿胆原。在用常规动物的粪便污染无菌动物后，无菌大鼠在相同饮食条件下产生尿胆素的程度与常规动物相同。在用从粪便中含有尿胆素的大鼠肠道内容物中分离出的一种单一类梭菌微生物感染无菌动物后，尿胆素阴性试验变为阳性。在用一株大肠杆菌进行重复感染后，这些单感染动物的尿胆素产量增加，但从未达到常规动物的水平。
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