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犬尿氨酸在果蝇脂肪体中的细胞内定位。

Intracellular localization of kynurenine in the fatbody of Drosophila.

作者信息

RIZKI M T

出版信息

J Biophys Biochem Cytol. 1961 Mar;9(3):567-72. doi: 10.1083/jcb.9.3.567.

DOI:10.1083/jcb.9.3.567
PMID:13741990
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2225016/
Abstract

Light blue fluorescent globules accumulate in the cells of the anterior region of the fatbody of Drosophila larvae near the time of pupation. This fluorescent material appears in the Ore-R wild type strain as well as mutant strains in which the synthesis of both the red and brown eye pigments is affected. The vermilion mutant, which is characterized by the absence of the brown pigment component in the eye, was the only strain among those examined which did not develop the light blue fluorescent globules. Utilizing chromatographic techniques together with the information gained by examination of the mutant strains, the fluorescent material has been identified as kynurenine. Of particular interest is the manner of appearance of the fluorescent material in the vicinity of the nuclear membrane of the fat cells.

摘要

在果蝇幼虫化蛹前不久,浅蓝色荧光小球会在脂肪体前部区域的细胞中积累。这种荧光物质在Ore-R野生型品系以及红色和棕色眼色素合成均受影响的突变品系中都会出现。朱砂眼突变体的特征是眼睛中缺乏棕色色素成分,是所检测的品系中唯一没有产生浅蓝色荧光小球的。利用色谱技术以及通过检测突变品系获得的信息,已将这种荧光物质鉴定为犬尿氨酸。特别令人感兴趣的是这种荧光物质在脂肪细胞核膜附近的出现方式。

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9
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本文引用的文献

1
Development of Eye Colors in Drosophila: Fat Bodies and Malpighian Tubes in Relation to Diffusible Substances.果蝇眼色的发育:与可扩散物质相关的脂肪体和马氏管
Genetics. 1937 Nov;22(6):587-611. doi: 10.1093/genetics/22.6.587.
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Development of Eye Colors in Drosophila: Diffusible Substances and Their Interrelations.果蝇眼色的发育:可扩散物质及其相互关系
Genetics. 1937 Jan;22(1):76-86. doi: 10.1093/genetics/22.1.76.
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Mutant Isoalleles at the Vermilion Locus in Drosophila Melanogaster.黑腹果蝇朱红基因座上的突变等位基因。
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Biochemical genetics of Bombyx mori (silkworm).家蚕的生化遗传学
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