孕期血清中N-乙酰-β-葡萄糖苷酶活性
N-acetyl-beta-glucosaminidase activity in serum during pregnancy.
作者信息
WALKER P G, WOOLLEN M E, PUGH D
出版信息
J Clin Pathol. 1960 Jul;13(4):353-7. doi: 10.1136/jcp.13.4.353.
Abstract
A spectrophotometric method for the estimation of N-acetyl-beta-glucosaminidase in serum has been devised. Sera from normal adult males and females showed similar levels of activity. The activity in serum rose progressively during pregnancy and fell rapidly after parturition to normal levels. This change resembled closely that which occurs in serum beta-glucuronidase. Placenta showed a moderate and chorion a high level of N-acetyl-beta-glucosaminidase. High N-acetyl-beta-glucosaminidase activity was demonstrated histochemically in decidual cells. The functions of N-acetyl-beta-glucosaminidase and beta-glucuronidase and factors influencing their activity are discussed.
摘要
已设计出一种用于测定血清中N-乙酰-β-氨基葡萄糖苷酶的分光光度法。正常成年男性和女性的血清显示出相似的活性水平。血清中的活性在怀孕期间逐渐升高，分娩后迅速下降至正常水平。这种变化与血清β-葡萄糖醛酸酶发生的变化非常相似。胎盘显示出中等水平的N-乙酰-β-氨基葡萄糖苷酶，而绒毛膜显示出高水平。在蜕膜细胞中通过组织化学方法证实了高N-乙酰-β-氨基葡萄糖苷酶活性。本文讨论了N-乙酰-β-氨基葡萄糖苷酶和β-葡萄糖醛酸酶的功能以及影响它们活性的因素。
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4
[Glycoside hydrolases in the human serum].
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5
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Serum hexosaminidase activity in I-cell disease carriers.
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8
Serum N-acetyl-beta-D-glucoasminidase and circulating immune complex activities in systemic lupus erythematosus.
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本文引用的文献
1
beta-Glucuronidase as an index of growth in the uterus and other organs.
Biochem J. 1949;44(4):487-94. doi: 10.1042/bj0440487.
2
The hydrolysis of glucosaminides by an enzyme in Helix pomatia.
Biochem J. 1939 Oct;33(10):1580-90. doi: 10.1042/bj0331580.
3
alpha-Glucosaminidase.
J Biol Chem. 1951 Aug;191(2):607-20.
4
Enzumatic formation of monosaccharides from hyaluronate.
J Biol Chem. 1955 Mar;213(1):237-48.
5
Influence of gonadectomy, sex hormones and other factors, on the activity of certain glycosidases in the rat and mouse.
J Endocrinol. 1959 Mar;18(2):132-46. doi: 10.1677/joe.0.0180132.
6
Glycosidases in mammalian sperm and seminal plasma.
Nature. 1957 Jun 8;179(4571):1190-1. doi: 10.1038/1791190a0.
7
Alpha-mannosidase and other glycosidases in the tissues of the mouse and the rat, with special reference to the sex organs.
Nature. 1956 Dec 29;178(4548):1469-70. doi: 10.1038/1781469a0.
8
Changes in the physical properties and in the collagen and hexosamine contents of the foetal membranes during pregnancy in the rat.
J Physiol. 1956 Jun 28;132(3):482-91. doi: 10.1113/jphysiol.1956.sp005541.
9
Uridine compounds in glucuronic acid metabolism. I. The formation of glucuronides in liver suspensions.
Biochem J. 1954 Jun;57(2):275-83. doi: 10.1042/bj0570275.
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