单胺氧化酶、精神振奋剂和镇静剂。
Monoamine oxidase, psychoenergizers, and tranquilizers.
作者信息
FELDSTEIN A, HOAGLAND H, FREEMAN H
出版信息
Science. 1959 Aug 28;130(3374):500. doi: 10.1126/science.130.3374.500.
PMID:13822065
Abstract
1-Benzyl-2-methyl-5-methoxytryptamine (BAS) inhibits monoamine oxidase in man. This finding confirms the findings of Woolley in mice. Since BAS, a tranquilizing agent, and Marsilid, a psychoenergizer, are both monoamine oxidase inhibitors, doubt is cast upon the hypothesis, that the stimulatory effect of Marsilid is due to its ability to inhibit monoamine oxidase.
摘要
1-苄基-2-甲基-5-甲氧基色胺（BAS）可抑制人体中的单胺氧化酶。这一发现证实了伍利在小鼠身上的研究结果。由于作为镇静剂的BAS和作为精神振奋剂的吗氯贝胺都是单胺氧化酶抑制剂，因此有人对吗氯贝胺的刺激作用是因其抑制单胺氧化酶的能力这一假说提出了质疑。
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