在无低氧情况下，益迷兴（香草酸二乙酰胺）对健康年轻男性二氧化碳呼吸反应的影响。
Effect of ethamivan (vanillic acid diethylamide) on the respiratory response of healthy young men to carbon dioxide, in the absence of hypoxia.
作者信息
ANDERTON J L, COWIE J F, HARRIS E A, SLEET R A
出版信息
Br J Pharmacol Chemother. 1962 Aug;19(1):142-52. doi: 10.1111/j.1476-5381.1962.tb01435.x.
The effect of ethamivan (vanillic acid diethylamide) on the ventilatory response to carbon dioxide has been investigated in healthy young adult males. Intravenous infusion of the drug at a rate of 9 mg/min causes respiratory stimulation depending in degree upon the prevailing alveolar CO(2) tension. When the latter is low stimulation by the drug is most marked and may largely support respiration below the CO(2) threshold. As alveolar Pco(2) increases, the effect of the drug disappears. These findings are discussed.
已在健康年轻成年男性中研究了香草二乙胺（香草酸二乙酰胺）对二氧化碳通气反应的影响。以9毫克/分钟的速率静脉输注该药物会引起呼吸刺激，刺激程度取决于当时的肺泡二氧化碳张力。当肺泡二氧化碳张力较低时，药物的刺激最为明显，并且在很大程度上可以维持低于二氧化碳阈值时的呼吸。随着肺泡二氧化碳分压升高，药物的作用消失。对这些发现进行了讨论。
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