Branley M G, Wright K W, Borchert M S
University of Southern California, Los Angeles.
Aust N Z J Ophthalmol. 1992 May;20(2):137-40. doi: 10.1111/j.1442-9071.1992.tb00726.x.
We report a case of cerebral aneurysm in a seven-year-old girl who presented with subacutely progressive third nerve palsy. To our knowledge this is the youngest reported patient with this condition. Confusion with myasthenia gravis occurred because of improvement in the patient's ptosis after intravenous edrophonium chloride. Cerebral CT revealed a hyperdense mass that was characterised on cerebral angiography as an aneurysm of the posterior communicating artery. Another occult aneurysm of the posterior cerebral artery was found at surgery. This case demonstrates that third nerve palsy due to cerebral aneurysm may affect patients at a younger age than has previously been recognised. Therefore we suggest that even young children should have aneurysm excluded by cerebral CT and angiography if they present with acquired third nerve palsy involving the pupil. In addition this case highlights the false-positive results that may occur with the edrophonium chloride test for myasthenia gravis.
我们报告一例七岁女孩的脑动脉瘤病例,该女孩表现为亚急性进行性动眼神经麻痹。据我们所知,这是报道的患有这种疾病的最年轻患者。由于静脉注射氯化依酚氯铵后患者上睑下垂有所改善,曾被误诊为重症肌无力。脑部CT显示一个高密度肿块,脑血管造影显示为后交通动脉瘤。手术中发现了另一例大脑后动脉隐匿性动脉瘤。该病例表明,脑动脉瘤导致的动眼神经麻痹可能影响比以往认识到的更年轻的患者。因此,我们建议,即使是幼儿,如果出现涉及瞳孔的后天性动眼神经麻痹,也应通过脑部CT和血管造影排除动脉瘤。此外,该病例突出了氯化依酚氯铵试验用于重症肌无力时可能出现的假阳性结果。