[两栖动物肝脏中的红细胞吞噬作用和色素细胞]

[Erythrophagocytosis and pigment cells of the amphibian liver].

作者信息

Kalashnikova M M

出版信息

Biull Eksp Biol Med. 1992 Jan;113(1):82-4.

Abstract

The ultrastructure of Kupffer liver cells of adult frogs collected in winter and Kupffer cells during amphibian metamorphosis when larval red cells are replaced by adult red cells were investigated. It was revealed that Kupffer cells of the animals investigated had very large size and consisted of either the whole senescent erythrocyte or many phagosomes with small electron dense granules resembling ferritin. Phagosomes are oriented among numerous vesicular and vermiform profiles of agranular endoplasmic reticulum and big Golgi complex. Comparing our morphologic evidence with data of the literature that granules of melanin are synthesized and localized in frog liver Kupffer cells, we came to conclusion that pigment cells were formed as a result of erythrophagocytosis and therefore they were the depo of catabolism products. The comparison of functions of melano-macrophage centers of fish liver and of pigment cells of amphibia liver were discussed.

摘要

对冬季采集的成年青蛙库普弗肝细胞以及两栖动物变态过程中（此时幼体红细胞被成体红细胞取代）的库普弗细胞的超微结构进行了研究。结果显示，所研究动物的库普弗细胞体积非常大，由整个衰老红细胞或许多含有类似铁蛋白的小电子致密颗粒的吞噬体组成。吞噬体排列在无颗粒内质网和大型高尔基体的众多泡状和蠕虫状结构之间。将我们的形态学证据与文献中关于黑色素颗粒在青蛙肝脏库普弗细胞中合成和定位的数据进行比较后，我们得出结论，色素细胞是红细胞吞噬作用的结果，因此它们是分解代谢产物的储存部位。还讨论了鱼肝黑素巨噬细胞中心与两栖动物肝色素细胞功能的比较。