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一项使用游离网膜移植促进新冠状动脉生长的手术:初步报告。

An operation designed to promote the growth of new coronary arteris, using a detached omental graft: a preliminary report.

作者信息

VINEBERG A, PIFARRE R, MERCIER C

出版信息

Can Med Assoc J. 1962 Jun 16;86(24):1116-8.

Abstract

The human greater omentum exhibits a marked affinity for inflamed surfaces, to which it supplies numerous blood vessels. To achieve myocardial revascularization by omental graft the root of the aorta, the epicardium over both ventricles and the serosal layer of the pericardium were removed in 17 animals. A piece of greater omentum was removed from the abdomen, unfolded and wrapped around the entire heart, and fixed by interrupted sutures to the base of the aorta. Myocardial ischemia was created at the time of operation by ameroid constriction of coronary arteries. Vessels, arteriolar or larger, were found to grow from the root of the aorta, the myocardium and the pericardium into the detached free omental graft, which apparently acted as a conveyer for new vessels, including new coronary arteries, to reach the myocardium.

摘要

人类大网膜对炎症表面表现出显著的亲和力,并向其供应大量血管。为通过网膜移植实现心肌血管重建,对17只动物切除了主动脉根部、两心室表面的心外膜和心包浆膜层。从腹部取下一片大网膜,展开后包裹整个心脏,并用间断缝合固定于主动脉根部。手术时通过冠状动脉阿霉素缩窄造成心肌缺血。发现从主动脉根部、心肌和心包长出的血管,无论是小动脉还是较大的动脉,都长入分离的游离网膜移植物中,该移植物显然充当了新血管(包括新的冠状动脉)到达心肌的输送载体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edf4/1849201/de1e8f81dd6e/canmedaj00948-0028-a.jpg

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