BISHOP M P, ELDER S T, HEATH R G
Science. 1963 Apr 26;140(3565):394-6. doi: 10.1126/science.140.3565.394.
Intracranial self-stimulation techniques, modified for use with neuropsychiatric patients, provide data suggestive of positive and negative reinforcing properties of brief electrical stimulation to various subcortical structures of the human brain.