Naether O
Geburtshilfe Frauenheilkd. 1992 Aug;52(8):494-5. doi: 10.1055/s-2007-1023796.
A patient with primary amenorrhoea was kept under hormonal replacement therapy and oral contraceptives since the age of sixteen. At the age of 30 she first consulted the endocrinologist because of infertility after one year of "post-pill-amenorrhoea". This first hormone check detected a severe hypertestosteronaemia (1.3 ng/ml). During four stimulation cycles using gonadotropins she showed a polyfollicular reaction and finally developed a hyperstimulation WHO II. During the following cycle she underwent hystero- and laparoscopy; laparoscopic electrocoagulation of the ovarian surface (LEOS) was carried out during this treatment. She subsequently conceived spontaneously twice.
一名原发性闭经患者自16岁起接受激素替代疗法和口服避孕药治疗。30岁时,因“停药后闭经”一年未孕,她首次咨询内分泌科医生。首次激素检查发现严重的高睾酮血症(1.3 ng/ml)。在使用促性腺激素的四个刺激周期中,她出现了多卵泡反应,最终发展为WHO II级卵巢过度刺激综合征。在接下来的周期中,她接受了子宫和腹腔镜检查;在此治疗过程中进行了腹腔镜卵巢表面电凝术(LEOS)。随后她自然受孕两次。