Kaabachi N, Fellah H, Abdelmoula J, Marrakchi O, Khrouf M, Mebazaa A
Laboratoire de Biochimie, CHU La Rabta Tunis, Tunisie.
J Gynecol Obstet Biol Reprod (Paris). 1992;21(5):544-8.
We analyzed the relationship between the evolution of pregnancy and the amplitude of the lipid disorders in order to evaluate their chronologic transformations. This research concerned 83 pregnancies aged between 19-40 years during the 3 periods of gestation and 31 healthy control women in the same range of age. Our results showed an increased triglyceride in the 2nd period and an earlier decrease of both, cholesterol, phospholipid and apolipoproteins. These parameters showed a progressive increase of their blood concentrations during the 2nd and the 3rd period of pregnancy, in an other hand we evidenced a good correlation between gestational aged and these variations i.e.: triglyceride and mother's weight; this phenomenon could suggest an eventual role of the nutrition and the hygienic habitude in the lipid metabolism. The correlation between our observed lipid disorders and the mother's age or the parity were not significant.
我们分析了孕期进展与脂质紊乱幅度之间的关系,以评估它们随时间的变化。本研究涉及83例年龄在19至40岁之间的孕妇,涵盖妊娠的三个阶段,以及31名年龄范围相同的健康对照女性。我们的结果显示,在妊娠第二期甘油三酯升高,而胆固醇、磷脂和载脂蛋白在更早阶段就开始下降。这些参数在妊娠第二和第三期血液浓度呈逐渐上升趋势,另一方面,我们证实胎龄与这些变化之间存在良好的相关性,即甘油三酯与母亲体重之间的相关性;这种现象可能表明营养和卫生习惯在脂质代谢中可能起到一定作用。我们观察到的脂质紊乱与母亲年龄或产次之间的相关性并不显著。