DEGABRIELE G
J Clin Pathol. 1963 Nov;16(6):569-72. doi: 10.1136/jcp.16.6.569.
In two groups of patients undergoing extracorporeal circulation with hypothermia, changes were found in the coagulation mechanism which were probably due to the dosage of polybrene administered. The role of heparin and polybrene and the concept of activation of the coagulation mechanism in the production of bleeding after perfusion are discussed.
在两组接受低温体外循环的患者中,发现凝血机制发生了变化,这可能与所使用的鱼精蛋白剂量有关。本文讨论了肝素和鱼精蛋白的作用以及灌注后出血过程中凝血机制激活的概念。