Joffe M, Avner J R
Emergency Department, St. Christopher's Hospital for Children, Temple University School of Medicine, Philadelphia, PA 19134-1095.
Pediatr Emerg Care. 1992 Oct;8(5):258-61. doi: 10.1097/00006565-199210000-00002.
Blood cultures are frequently obtained in pediatric emergency departments (EDs) from febrile young children at risk for bacteremia and subsequent development of serious bacterial infections. This study of 105 children with occult bacteremia treated in two large urban pediatric EDs describes the follow-up of these patients and the impact that positive blood culture results have on the detection of serious illness. Seventy-seven percent of patients had a follow-up visit in the ED, 8% had follow-up by telephone alone, and 15% were not contacted. Of the patients who returned to the ED, 49% did so because they were notified of the positive blood culture result. The mean time interval for these patients from registration at the initial visit to report of positive blood culture result was 30.0 hours and, from registration at the initial visit to follow-up visit, was 42.7 hours. Thirty-seven percent of those who returned did so because a follow-up visit was scheduled at the initial encounter, and 13% returned because of persistent illness. Ten children (9.6%), five of whom had been notified of the positive blood culture, returned with serious illnesses. Patients whose diagnosis of serious illness was facilitated by blood culture results had shorter delay in identifying cultures as positive than did patients notified of positive results who did not develop serious illness (16.2 vs 31.6 hours; P < 0.05). The delay in follow-up of children with occult bacteremia limits the usefulness of blood cultures in the early detection of serious illness.(ABSTRACT TRUNCATED AT 250 WORDS)
在儿科急诊科(EDs),经常会对有菌血症风险及随后发生严重细菌感染风险的发热幼儿进行血培养。这项对在两家大型城市儿科急诊科接受治疗的105例隐匿性菌血症患儿的研究,描述了这些患者的随访情况以及血培养阳性结果对严重疾病检测的影响。77%的患者在急诊科进行了随访,8%仅通过电话进行随访,15%未被联系。在返回急诊科的患者中,49%是因为被告知血培养结果呈阳性而返回。这些患者从初次就诊登记到血培养结果呈阳性报告的平均时间间隔为30.0小时,从初次就诊登记到随访就诊的平均时间间隔为42.7小时。37%返回的患者是因为在初次就诊时安排了随访,13%返回是因为疾病持续存在。10名儿童(9.6%)返回,其中5名已被告知血培养阳性,他们患有严重疾病。血培养结果有助于诊断严重疾病的患者,其识别培养结果为阳性的延迟时间比被告知阳性结果但未发生严重疾病的患者短(16.2小时对31.6小时;P<0.05)。隐匿性菌血症患儿随访的延迟限制了血培养在严重疾病早期检测中的作用。(摘要截短至250字)