THE EFFECT OF CERTAIN ETHYLENEIMINES ON RENAL FUNCTION.
作者信息
JACKSON H, JAMES R M
出版信息
Br J Pharmacol Chemother. 1963 Dec;21(3):581-9. doi: 10.1111/j.1476-5381.1963.tb02025.x.
Abstract
Certain simple derivatives of ethyleneimine cause an intense and prolonged diuresis in nonhydrated rats. Sodium, potassium and chloride excretion is unaffected by these compounds. Ethyleneimine also causes a diuresis in the rat, but the polyfunctional compound thiotepa is ineffective. The relationship between structure and activity of a number of compounds is discussed with particular reference to the possibility that the diuresis is due to the in vivo liberation of ethyleneimine.
摘要
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引用本文的文献
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