Gaillard-Perera H, Gaillard A
Stomatologiste des Hôpitaux, Hôtel-Dieu, Nantes.
Rev Stomatol Chir Maxillofac. 1992;93(5):327-32.
Bucco-facial dyskinesia is particularly frequent in aged persons, for whom the condition is a definite handicap because of its social and, sometimes, functional impact. The etiology of these abnormal movements is variable. On one hand, many treatments can be incriminated, especially neuroleptics, and on the other hand, there also are frequent spontaneous dyskinesias, movements for which the risk factors are described. The physiopathology remains open to discussion and research, but we already know that the regulation of the nigro-striated pathway plays a role in it, as well, maybe, as toxic (free radicals) and immunological factors. Various therapies are described, but the outcome for such dyskinesias is often unfavorable, at least in elderly subjects, hence the merits of prevention. The latter is based on the prescription of as few neuroleptic drugs as possible, on the use of possibly protective substances, and finally on the suppression on the triggering elements that some local factors may form.
口面部运动障碍在老年人中尤为常见,由于其对社交以及有时对功能的影响,这种情况对老年人来说是一种明确的障碍。这些异常运动的病因多种多样。一方面,许多治疗方法可能会引发这种情况,尤其是抗精神病药物,另一方面,也经常会出现自发性运动障碍,其风险因素已被描述。其生理病理学仍有待讨论和研究,但我们已经知道黑质纹状体通路的调节在其中也起作用,也许还有毒性(自由基)和免疫因素。文中描述了各种治疗方法,但这种运动障碍的预后通常不佳,至少在老年患者中是这样,因此预防很有必要。预防基于尽可能少地使用抗精神病药物、使用可能具有保护作用的物质,以及最后消除一些局部因素可能形成的触发因素。