ESPINOSA E, CANELO E, BRAVO M, GONZALEZ O
Science. 1964 Apr 24;144(3617):417-8. doi: 10.1126/science.144.3617.417.
Agar electrophoresis of serum from mice of C57BL/10-H-2(d), B10.Sn, A.SW, A.CA, R III, and P1 inbred strains shows that the females have a lower concentration of alpha-1 serum globulin than the males and, in some strains, the females also have a lower concentration of alpha-2 and, beta-serum globulin. Females of the A.SW strain have a higher serum albumin concentration than males, and females of the C57BL/10-H-2(d) strain have a higher gamma-globulin concentration than males. Two-dimensional (agar and hydrolyzed-starch) electrophoresis gives a typical sex-associated pattern for alpha-1 and alpha-2 globulins which clearly permits recognition of male and female serums.
对C57BL/10-H-2(d)、B10.Sn、A.SW、A.CA、R III和P1近交系小鼠血清进行琼脂电泳显示,雌性小鼠的α-1血清球蛋白浓度低于雄性,并且在某些品系中,雌性小鼠的α-2和β-血清球蛋白浓度也较低。A.SW品系的雌性小鼠血清白蛋白浓度高于雄性,而C57BL/10-H-2(d)品系的雌性小鼠γ-球蛋白浓度高于雄性。二维(琼脂和水解淀粉)电泳给出了α-1和α-2球蛋白典型的性别相关图谱,能够清晰地识别雄性和雌性血清。