Sahgal A, Galloway P H, McKeith I G, Lloyd S, Cook J H, Ferrier I N, Edwardson J A
Medical Research Council Neurochemical Pathology Unit, Newcastle General Hospital, Newcastle upon Tyne, England.
Arch Neurol. 1992 Oct;49(10):1043-6. doi: 10.1001/archneur.1992.00530340059019.
Using a computerized matching-to-sample task, nonverbal visual recognition memory was studied in two groups of patients suffering from senile dementia of the Alzheimer type or the recently described senile dementia of the Lewy body type. The patients' cognitive abilities had been shown to be similar according to a number of standard psychometric tests. The two groups did not differ with respect to simultaneous matching-to-sample performance, although both were impaired relative to control. The group with senile dementia of the Lewy body type was severely impaired, relative to the group with senile dementia of the Alzheimer type, when delays (delayed matching to sample) were introduced. The findings suggest that short-term mnemonic processes, mediated by temporal lobe structures, could be more severely affected in senile dementia of the Lewy body type.
采用计算机化的匹配样本任务，对两组患有阿尔茨海默型老年痴呆症或最近描述的路易体型老年痴呆症的患者进行了非言语视觉识别记忆研究。根据多项标准心理测量测试，已证明这两组患者的认知能力相似。两组在同时进行匹配样本任务的表现上没有差异，尽管相对于对照组两者都有损害。当引入延迟（延迟匹配样本）时，路易体型老年痴呆症组相对于阿尔茨海默型老年痴呆症组受到严重损害。研究结果表明，由颞叶结构介导的短期记忆过程在路易体型老年痴呆症中可能受到更严重的影响。
