SHANE S J, ATERMAN K, ROY D L, CHANDLER B M
Can Med Assoc J. 1964 Jul 25;91(4):145-53.
Primary pulmonary hypertension can no longer be considered an uncommon disorder. Five patients with this disorder seen over a comparatively short period of time are reported. All were young women, whose symptomatology and laboratory findings are described. No other disorder was found associated with or responsible for the increase in pulmonary vascular pressure. In two instances the diagnosis was confirmed at necropsy, and a detailed description of the pathological findings in one of these cases is given. Some of the pertinent clinical and pathological literature on the subject of primary pulmonary hypertension is reviewed, and the current findings are discussed in the context of this literature.
原发性肺动脉高压再也不能被视为一种罕见疾病了。本文报告了在相对较短时间内接诊的5例患有该疾病的患者。所有患者均为年轻女性,文中描述了她们的症状和实验室检查结果。未发现其他疾病与肺动脉压力升高有关或可导致肺动脉压力升高。其中2例在尸检时确诊,本文给出了其中1例病例详细的病理检查结果描述。本文回顾了一些关于原发性肺动脉高压的相关临床和病理文献,并结合这些文献对当前的研究结果进行了讨论。