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[AKR小鼠的自发性白血病。用抗Friend白血病病毒分离糖蛋白gp71的山羊抗体成功进行被动免疫]

[Spontaneous leukemia of AKR mice. Successful passive immunization with goat antibodies against isolated glycoprotein gp71 of Friend leukemia virus].

作者信息

Schwarz H, Thiel H J, Schäfer W

出版信息

Z Naturforsch C Biosci. 1977 May-Jun;32(5-6):459-61.

PMID:141818
Abstract

The occurrence of fatal spontaneous leukemia in AKR mice could be drastically reduced by passive immunization with goat antibody against isolated murine Friend virus glycoprotein gp71, possessing high group specific reactivity. The success depended on the time of antibody application. The best results were achieved when mothers and babies were inoculated.

摘要

用针对分离出的具有高群特异性反应性的鼠类弗氏病毒糖蛋白gp71的山羊抗体进行被动免疫,可大幅降低AKR小鼠致命性自发性白血病的发生率。成功与否取决于抗体施用的时间。当对母鼠和幼鼠进行接种时,能取得最佳效果。

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