ROSEN I B, SHAPIRO B J
Can Med Assoc J. 1964 Sep 26;91(13):681-8.
The features of radiation injury of the small bowel are reviewed to focus attention on this uncommon but persistent problem which usually arises in women undergoing treatment for gynecological malignancy and which may be confused with recurrence of the malignant growth. Intestinal perforation, bleeding, obstruction and fistulas have all been observed in patients with radiation enteropathy. Three cases in which these complications occurred are reported. Early excisional surgery is considered to be the preferred treatment, although conservative surgical procedures have been used for patients who are very ill or for those with diffuse bowel changes. Medical measures alone have not been successful but have been utilized in preoperative preparation.
本文回顾了小肠放射性损伤的特征,以引起人们对这个虽不常见但持续存在的问题的关注。该问题通常发生在接受妇科恶性肿瘤治疗的女性身上,可能会与恶性肿瘤复发相混淆。放射性肠炎患者中已观察到肠穿孔、出血、梗阻和瘘管等情况。报告了3例出现这些并发症的病例。早期切除手术被认为是首选治疗方法,不过对于病情非常严重或肠道有弥漫性改变的患者,也采用了保守性手术操作。单独的药物治疗尚未取得成功,但已用于术前准备。