LEONARD D J, ZAVALA A
Science. 1964 Nov 20;146(3647):1073-4. doi: 10.1126/science.146.3647.1073.
If electroconvulsive shock is given immediately after a learning session, retroactive amnesia for that response occurs. Such results may be due to production of aversive responses or to interference with consolidation of the neural engram, or to both. Aversive responses or competing responses are not adequate explanations for retroactive amnesia. Consolidation theory provides the most plausible explanation. The single-shock method is an appropriate approach for studying the relationships between electroconvulsive shock and retroactive amnesia.
如果在一次学习活动之后立即给予电休克,就会出现对该反应的逆行性遗忘。这样的结果可能是由于产生了厌恶反应,或者是干扰了神经记忆痕迹的巩固,或者两者皆有。厌恶反应或竞争性反应并不能充分解释逆行性遗忘。巩固理论提供了最合理的解释。单次电击法是研究电休克与逆行性遗忘之间关系的一种合适方法。