SMITH A, FARBMAN A, DANCIS J
Science. 1965 Feb 26;147(3661):1040-1. doi: 10.1126/science.147.3661.1040.
No fungiform papillae could be found on the tongues of 30 patients with familial dysautonomia. In ten of these patients a search for vallate papillae was made, but none were found. Inspection of the tongue may thus be useful for diagnosing this rare disease, even in infants. Absence of these sensory receptors suggests that the multiple sensory deficits found in persons with familial dysautonomia may be related to defects in the peripheral receptors.
在30例家族性自主神经功能异常患者的舌头上未发现菌状乳头。在其中10例患者中寻找轮廓乳头,但未发现。因此,即使对婴儿来说,检查舌头也可能有助于诊断这种罕见疾病。这些感觉感受器的缺失表明,家族性自主神经功能异常患者中发现的多种感觉缺陷可能与外周感受器的缺陷有关。