NICKLAS R B, JAQUA R A
Science. 1965 Feb 26;147(3661):1041-3. doi: 10.1126/science.147.3661.1041.
The X chromosome in Melanoplus differentialis is negatively heteropycnotic in the early spermatogonial cell generations but positively heteropycnotic in the final premeiotic interphase. Autoradiography after administration of tritiated thymidine reveals that this condensation change is paralleled by a change in the time of DNA replication in the X chromosome relative to that in the autosomes.
在不同黑蝗中,X染色体在精原细胞早期世代呈负异固缩,但在减数分裂前的最后间期呈正异固缩。给予氚标记胸腺嘧啶核苷后进行放射自显影显示,这种凝聚变化与X染色体相对于常染色体的DNA复制时间变化是平行的。