在一名两性畸形婴儿中通过荧光原位杂交（FISH）鉴定出多条源自Y染色体的微小标记染色体。
Multiple minute marker chromosomes derived from Y identified by FISH in an intersexual infant.
作者信息
Diekmann L, Palm K, Pfeiffer R A, Trautmann U, Scholz W, Schroers E, Vogt P, Köhler M
机构信息
Städtische Kinderklinik, Dortmund, Federal Republic of Germany.
出版信息
Hum Genet. 1992 Sep-Oct;90(1-2):181-3. doi: 10.1007/BF00210772.
PMID:1427776
Abstract
Chromosomal analysis in a child with ambiguous sex showed mosaicism of at least two cell lines with one or more marker chromosomes or none at all. They were shown to be derived from the Y chromosome by fluorescent in situ hybridisation (FISH) using different DNA probes that cover parts of the long and the short arm.
摘要
对一名性征模糊的儿童进行染色体分析显示，至少有两条细胞系存在嵌合体，伴有一条或多条标记染色体，或根本没有标记染色体。通过使用覆盖长臂和短臂部分的不同DNA探针进行荧光原位杂交（FISH），证实它们源自Y染色体。
Zotero 插件