白足鼠中葡萄糖-6-磷酸脱氢酶的常染色体决定多态性
AUTOSOMALLY DETERMINED POLYMORPHISM OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN PEROMYSCUS.
作者信息
SHAW C R, BARTO E
出版信息
Science. 1965 May 21;148(3673):1099-100. doi: 10.1126/science.148.3673.1099.
Abstract
Glucose-6-phosphate dehydrogenase commonly occurs in at least two forms in most tissues of the deer mouse, Peromyscus maniculatus, as demonstrated by starch-gel electrophoresis. An autosomally determined genetic polymorphism in one of the enzymes was discovered. A hybrid molecule occurs in the heterozygote; this suggests a dimeric structure of this enzyme.
摘要
通过淀粉凝胶电泳表明，葡萄糖-6-磷酸脱氢酶在鹿鼠（白足鼠）的大多数组织中通常至少以两种形式存在。在其中一种酶中发现了由常染色体决定的遗传多态性。杂合子中出现了一种杂交分子；这表明该酶具有二聚体结构。
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