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二尖瓣疾病的心脏直视手术

OPEN-HEART SURGERY FOR MITRAL VALVE DISEASE.

作者信息

GEREIN A N, GOURLAY R H, KAVANAGH-GRAY D

出版信息

Can Med Assoc J. 1965 Sep 18;93(12):643-50.

Abstract

The findings in and experiences with 19 consecutive patients subjected to open mitral valve surgery are described. All patients underwent a right-heart catheterization. In order to exclude multivalvular heart disease, a left-heart catheterization was performed in 10 patients and angiographic studies of the aortic valve area in 12. Pulmonary function studies were performed on 11 patients. The FEV (0.75 sec.) and the MMFR were found to correlate well with existing pulmonary reserves.Fourteen of the 19 patients subjected to open mitral valve surgery survived the operation and have been followed up for three months to 2(1/2) years. Four patients had a mitral valvuloplasty. Three of these four have deteriorated and will require a valvular replacement. Ten of 15 patients subjected to a mitral valve replacement are alive; five of these 10 have had signs and symptoms indicating peripheral embolization. Mitral valvuloplasty is preferable to a valvular replacement as far as embolic complications are concerned, while valvular replacements result in a more perfect and lasting hemodynamic repair. The high incidence of peripheral embolization following valvular replacements focuses attention on the need for improved mitral valve prostheses.

摘要

本文描述了19例接受二尖瓣开放手术患者的研究结果和经验。所有患者均接受了右心导管检查。为排除多瓣膜心脏病,10例患者进行了左心导管检查,12例进行了主动脉瓣区域的血管造影研究。11例患者进行了肺功能研究。发现第一秒用力呼气量(0.75秒)和最大呼气中期流速与现有的肺储备功能密切相关。19例接受二尖瓣开放手术的患者中有14例术后存活,随访时间为3个月至2年半。4例患者接受了二尖瓣成形术。这4例中的3例病情恶化,需要进行瓣膜置换。15例接受二尖瓣置换术的患者中有10例存活;这10例中的5例出现了提示周围栓塞的体征和症状。就栓塞并发症而言,二尖瓣成形术优于瓣膜置换术,而瓣膜置换术能带来更完美和持久的血流动力学修复。瓣膜置换术后周围栓塞的高发生率引起了人们对改进二尖瓣假体的关注。

引用本文的文献

1
Valvoplasty for abnormalities of posterior (mural) cusp of the mitral valve.
Thorax. 1968 Nov;23(6):608-20. doi: 10.1136/thx.23.6.608.

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