Grapin C, Audry G, Bensman A, Bruézière J, Gruner M
Service d'Urologie Pédiatrique, Hôpital Trousseau, Paris.
Ann Urol (Paris). 1992;26(4):256-60.
The renal transplantation in children has some specificities: urologic anomalies (vesico ureteral reflux, posterior urethral valves) are frequently the cause of the renal failure, and necessitate a thorough surgical preparation before transplantation (nephrectomy, reconstitution of urinary tract). The child must have a sterile, compliant and continent urinary tract on the day of the operation. In small children (< 15 kg), it is often necessary to operate through a transperitoneal incision, especially if the donor is an adult: the anastomoses will then concern the aorta and vena cava. The results are good, even better than in adults, except for very young children (under six years of age). Transplantation with living related donor (LRD) give the best results. Currently, the graft survival is 87% to 90% after three years with LRD, versus 65 to 77% with cadaveric donors.
泌尿系统异常(膀胱输尿管反流、后尿道瓣膜)常常是肾衰竭的病因,并且在移植前需要进行全面的外科准备(肾切除术、尿路重建)。患儿在手术当天必须拥有无菌、顺应性良好且无尿失禁的尿路。对于体重小于15千克的幼儿,通常需要经腹切口进行手术,尤其是当供体为成人时:此时吻合将涉及主动脉和腔静脉。除了极小的儿童(六岁以下),手术效果良好,甚至优于成人。活体亲属供体(LRD)移植的效果最佳。目前,活体亲属供体移植三年后的移植物存活率为87%至90%,而尸体供体移植的存活率为65%至77%。