Acute disseminated encephalomyelitis, with massive necrosis of the spinal cord, probably due to antitetanus serum.

The clinical and pathological findings are described of a fatal case of acute haemorrhagic leucoencephalitis and disseminated encephalomyelitis with acute necrosis of the white matter of the spinal cord. It is suggested that the reaction was a severe immunological response of an allergic nature, probably due to antitetanus serum.