MITCHELL E S
J Clin Pathol. 1962 May;15(3):231-4. doi: 10.1136/jcp.15.3.231.
During an 18-month period 1,002 strains of Streptococcus pyogenes, consecutively isolated in the laboratory from a wide variety of lesions, were typed by the precipitin and slide-agglutination tests. The relative frequency of serotypes in different diseases was examined and a close association between type 4 in scarlet fever and type 3.13 in impetigo noted. An apparent lack of any relationship between particular serotypes and streptococcal sore throat was evident. The difficulty of distinguishing the more virulent types of Str. pyogenes and correlating a type-specific disease relationship is discussed.
在18个月的时间里,从实验室中连续分离出1002株化脓性链球菌,这些菌株来自各种各样的病变部位,通过沉淀素试验和玻片凝集试验进行分型。研究了不同疾病中血清型的相对频率,并注意到猩红热中的4型与脓疱病中的3.13型之间存在密切关联。明显缺乏特定血清型与链球菌性咽喉炎之间的任何关系。讨论了区分化脓性链球菌更具毒力的类型以及将特定类型与疾病关系相关联的困难。