Pellon R, Blackman D E
Facultad de Psicologia, Universidad Nacional de Educacion a Distancia, Madrid, Spain.
Pharmacol Biochem Behav. 1992 Nov;43(3):689-95. doi: 10.1016/0091-3057(92)90397-x.
Drinking was induced in food-deprived rats by a fixed-time 1-min schedule of food presentation. With three rats, d-amphetamine (0.25, 0.5, 1.0, and 2.0 mg/kg) led to a dose-related increase in licking early in the interfood intervals, the peak of the temporal distribution of licking being shifted to earlier values. These effects were seen even when d-amphetamine had no effect on overall rates of licking and drinking. With another three rats, however, diazepam (0.5, 1.0, 2.0, and 4.0 mg/kg) did not shift the peak of the temporal distribution of licks in interfood intervals, even at doses that produced small increases in overall rates of licking and drinking. However, diazepam did reduce the peak of the distributions of licks at doses that did not decrease water intake and licks per minute.
在食物匮乏的大鼠中，通过定时1分钟的食物呈现时间表诱导其饮水行为。对于三只大鼠，d-苯丙胺（0.25、0.5、1.0和2.0毫克/千克）导致在食物间隔早期舔舐行为呈剂量相关增加，舔舐时间分布的峰值提前。即使d-苯丙胺对舔舐和饮水的总体速率没有影响，这些效应依然可见。然而，对于另外三只大鼠，地西泮（0.5、1.0、2.0和4.0毫克/千克）即使在导致舔舐和饮水总体速率略有增加的剂量下，也未改变食物间隔期间舔舐时间分布的峰值。不过，地西泮在不减少每分钟饮水量和舔舐次数的剂量下，确实降低了舔舐分布的峰值。
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