大鼠乳腺体外催产素测定法。
Assay of oxytocin by rat mammary gland in vitro.
作者信息
RYDEN G, SJOHOLM I
出版信息
Br J Pharmacol Chemother. 1962 Aug;19(1):136-41. doi: 10.1111/j.1476-5381.1962.tb01434.x.
Abstract
A new method for quantitative assay of oxytocin using strips from rat mammary gland in vitro has been investigated. The method is very suitable for determination of small amounts of oxytocin. Doses down to 2 mu-u. oxytocin have been estimated. The dose-response curve is shown to be linear, and the precision of the method is good (lambda =0.10 to 0.14). The effect of adrenaline, noradrenaline, acetylcholine, histamine and 5-hydroxytryptamine on the rat mammary gland has also been tested.
摘要
研究了一种利用大鼠乳腺条带体外定量测定催产素的新方法。该方法非常适合测定少量催产素。已对低至2微单位的催产素剂量进行了估算。剂量-反应曲线呈线性，且该方法的精密度良好（λ=0.10至0.14）。还测试了肾上腺素、去甲肾上腺素、乙酰胆碱、组胺和5-羟色胺对大鼠乳腺的作用。
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