Silove Derrick, Blaszczynski Alex, Manicavasager Vijaya, Tyndall Karen, Petridis Angela, Hillman Ken
Psychiatry Research and Teaching Unit, School of Psychiatry, University of New South Wales, Liverpool Hospital, Liverpool, Australia.
J Nerv Ment Dis. 2003 Sep;191(9):604-10. doi: 10.1097/01.nmd.0000087187.13408.e1.
Motor vehicle accidents are one of the most common causes of trauma-related psychiatric morbidity. Previous studies have suggested that symptom screening instruments may be useful in predicting risk of longer-term psychiatric morbidity, but results have varied. The present study is based on 83 of an eligible 102 consecutive hospital-admitted survivors of road trauma who completed a structured clinical interview at baseline and 18-month follow-up. A subsample returned symptom questionnaires within 2 weeks of the accident, with between 60 and 66 completing the questionnaire. Receiver Operator Characteristic curve analyses were applied to obtain optimal predictive scores on each screening measure. Combining the derived cutoff scores on the Impact of Event Scale (measuring posttraumatic stress disorder symptoms) and the Beck Depression Inventory yielded an odds ratio of 82.9 in predicting any psychiatric morbidity at 18 months, with a specificity of 95%, and high positive (89%) and negative (91%) predictive indices. If these exploratory findings are confirmed by future studies, the case will be strengthened for routine screening of motor vehicle accident survivors to allow ongoing monitoring and selective early interventions for the high-risk subgroup. Compliance with completing and returning questionnaires remains a major challenge in this population, however, as indicated by the level of attrition in our study.
机动车事故是创伤相关精神疾病最常见的病因之一。以往研究表明,症状筛查工具可能有助于预测长期精神疾病的风险,但结果各不相同。本研究基于102名符合条件的连续入院道路创伤幸存者中的83名,他们在基线和18个月随访时完成了结构化临床访谈。一个子样本在事故发生后2周内返回了症状问卷,有60至66人完成了问卷。应用受试者工作特征曲线分析以获得每种筛查措施的最佳预测分数。将事件影响量表(测量创伤后应激障碍症状)和贝克抑郁量表得出的临界值分数相结合,在预测18个月时的任何精神疾病方面,优势比为82.9,特异性为95%,阳性预测指数高(89%),阴性预测指数高(91%)。如果这些探索性结果得到未来研究的证实,那么对机动车事故幸存者进行常规筛查以对高危亚组进行持续监测和选择性早期干预的理由将更加充分。然而,正如我们研究中的损耗水平所示,在这一人群中,完成并返回问卷的依从性仍然是一个重大挑战。