金黄色葡萄球菌肺炎治疗后由JK组棒状杆菌引起的致命性肺炎。

Fatal pneumonia caused by Corynebacterium group JK after treatment of Staphylococcus aureus pneumonia.

作者信息

Yoshitomi Y, Kohno S, Koga H, Maesaki S, Higashiyama Y, Matsuda H, Mitsutake K, Miyazaki Y, Yamada H, Hara K

机构信息

Second Department of Internal Medicine, Nagasaki University School of Medicine, Japan.

出版信息

Intern Med. 1992 Jul;31(7):930-2. doi: 10.2169/internalmedicine.31.930.

DOI:10.2169/internalmedicine.31.930

PMID:1450504

Abstract

A 76-year-old man who was admitted to the hospital because of chronic renal insufficiency and chronic hepatitis died of Corynebacterium group JK pneumonia, after showing a slight improvement by treatment of Staphylococcus aureus with sulbactam/cefoperazone and minocycline. Transtracheal aspiration (TTA) just before his death revealed numerous gram-positive bacilli phagocytized by many neutrophils and more than 10(8) colony forming units (CFU)/ml of Corynebacterium group JK. A drug susceptibility test showed Corynebacterium group JK was resistant to many antibiotics, with the exception of vancomycin and amikacin.

摘要

一名因慢性肾功能不全和慢性肝炎入院的76岁男性，在使用舒巴坦/头孢哌酮和米诺环素治疗金黄色葡萄球菌后病情稍有改善，但最终死于JK组棒状杆菌肺炎。临死前经气管穿刺吸引术（TTA）显示有大量被许多中性粒细胞吞噬的革兰氏阳性杆菌，JK组棒状杆菌的菌落形成单位（CFU）超过10⁸/ml。药敏试验显示JK组棒状杆菌对许多抗生素耐药，仅对万古霉素和阿米卡星敏感。