Dosumu E A
Department of Medicine, Respiratory Unit, Faculty of Health Sciences, University of Ilorin, Nigeria.
Afr J Med Med Sci. 2001 Mar-Jun;30(1-2):111-4.
Five hundred newly diagnosed cases of pulmonary tuberculosis patients were studied at Iwo Local Government tuberculosis (TB) control clinic Alaye, Iwo, Osun state of Nigeria. The study was to determine (a) the rate of compliance to antituberculous drugs in newly diagnosed pulmonary tuberculosis (PTB) patients over a 2-year period in Iwo, Nigeria treated with directly observed treatment short-course (DOTS). DOTS is a short course treatment lasting 6-8 months and (b) the effect of DOTS and the use of home visitors on compliance with a view to formulating a model that can be used all over Nigeria to stem the resurgence of PTB. All newly diagnosed cases of PTB at Iwo, Osun state of Nigeria were treated with DOTS over a two-year period. TB home visitor provided with a motorcycle was used throughout the treatment period with free drug provision by Damien Foundations of Belgium based in Ibadan, Nigeria. The rate of compliance was noted in all cases. Total (100 percent) compliance and cure rate were recorded with the use of DOTS and TB home visitor in this study. The home visitor carried out 50 visitations during the study period. The use of DOTS with free drug provision and the use of home visitor as used in this study confirmed its effectiveness in enhancing compliance and hence cure of PTB. The study is a model that can be adopted for the whole of Nigeria and other countries globally if tuberculosis must be controlled.
在尼日利亚奥孙州伊沃市阿拉耶的伊沃地方政府结核病控制诊所,对500例新诊断的肺结核患者进行了研究。该研究旨在确定:(a) 在尼日利亚伊沃市,采用直接观察短程治疗(DOTS)对新诊断的肺结核(PTB)患者进行为期2年的抗结核药物治疗的依从率。DOTS是一种为期6 - 8个月的短程治疗方法;(b) DOTS及家访员的使用对依从性的影响,以期制定一个可在尼日利亚全境使用的模式,以遏制PTB的复发。在两年时间里,尼日利亚奥孙州伊沃市所有新诊断的PTB病例均采用DOTS进行治疗。在整个治疗期间,配备摩托车的结核病家访员参与其中,由位于尼日利亚伊巴丹的比利时达米恩基金会提供免费药物。记录了所有病例的依从率。在本研究中,采用DOTS和结核病家访员实现了100%的总依从率和治愈率。家访员在研究期间进行了50次家访。本研究中使用的DOTS、免费药物供应以及家访员的使用,证实了其在提高依从性从而治愈PTB方面的有效性。如果要控制结核病,该研究模式可在尼日利亚全境及全球其他国家采用。