Su Xiao-hui, Liu Shou-jun, Sun Shu-qiu, Ye Yong-xiang, Liu Ying
Institute for Iodine Deficiency Disorders Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin 150086, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2003 Sep;24(9):787-9.
To study the factors leading to the variation of children's total goiter rates, urine iodine and salt iodine in West China.
Design effect (DEFF) was used to evaluate the variation of indicators.
DEFF of children's total goiter rate was about 3.0 in 9 provinces, and the proportion was 75.0%. The DEFF of urine iodine was 1.0 - 3.5 in 6 provinces, and the proportion was 50.0%. The DEFF of intake rate of qualified iodized salt was over 3.0 in 11 provinces. The DEFF of covering rate of iodized salt was about 3.0 in 4 provinces.
In order to provide scientific basis for IDD surveillance in China, other than bias due to methods of no-sampling, sample size should be further calculated in West China. Thus the main influencing factors of indicator variation could be measured with scientific and reasonable basis.
研究中国西部儿童甲状腺肿大率、尿碘和盐碘变化的影响因素。
采用设计效应（DEFF）评估指标的变化情况。
9个省份儿童甲状腺肿大率的设计效应约为3.0，占比75.0%。6个省份尿碘的设计效应为1.0 - 3.5，占比50.0%。11个省份合格碘盐食用率的设计效应超过3.0。4个省份碘盐覆盖率的设计效应约为3.0。
为给中国碘缺乏病监测提供科学依据，除无抽样方法导致的偏倚外，中国西部还应进一步计算样本量，以便科学合理地测定指标变化的主要影响因素。
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