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影响接受闭式二尖瓣交界切开术患者手术结果的超声心动图变量。

Echocardiographic variables affecting surgical outcome in patients undergoing closed mitral commissurotomy.

作者信息

Prasad K, Radhakrishnan S

机构信息

Department of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

出版信息

Int J Cardiol. 1992 Nov;37(2):237-42. doi: 10.1016/0167-5273(92)90214-n.

Abstract

We studied, by transthoracic cross-sectional echocardiography, the influence of subvalvar pathology on the early hemodynamic result of closed mitral commissurotomy in 132 patients with severe rheumatic mitral stenosis (56 males, 76 females, mean age 25.2 yr, range 10-55) in our tertiary care hospital in North India from July 89 to December 91. The mitral subdistance ratio was calculated by dividing the distance between the papillary muscle tip and mitral valve in systole (apical 4-chamber view) by left ventricular diastolic length (apical long axis view). Nineteen patients with mild subvalvar pathology (mitral subdistance ratio > 0.18) and 71 patients with moderate, achieved a larger valve area (2.26 cm2 SD 0.54) than 42 patients with severe subvalvar pathology (mitral subdistance ratio < 0.12, postoperative valve area 2.09 cm2 SD 0.6, p < 0.05). In addition, 9 of these 42 patients (21%) developed significant mitral regurgitation (4 deaths), in contrast to 1/19 with mild and 6/71 with moderate subvalvar pathology. We conclude that echocardiography identifies patients with severe subvalvar pathology who fare poorly after closed mitral commissurotomy. However, this procedure would still be practised in developing countries like ours due to financial constraints.

摘要

1989年7月至1991年12月,在印度北部的一家三级护理医院,我们通过经胸横断面超声心动图研究了132例重度风湿性二尖瓣狭窄患者(56例男性,76例女性,平均年龄25.2岁,范围10 - 55岁)瓣下病变对闭式二尖瓣交界分离术早期血流动力学结果的影响。二尖瓣瓣下距离比的计算方法是,将收缩期乳头肌尖端与二尖瓣之间的距离(心尖四腔心切面)除以左心室舒张期长度(心尖长轴切面)。19例轻度瓣下病变患者(二尖瓣瓣下距离比>0.18)和71例中度瓣下病变患者术后瓣膜面积较大(2.26 cm²±0.54),大于42例重度瓣下病变患者(二尖瓣瓣下距离比<0.12,术后瓣膜面积2.09 cm²±0.6,p<0.05)。此外,这42例患者中有9例(21%)出现了严重二尖瓣反流(4例死亡),而轻度瓣下病变患者中为1/19,中度瓣下病变患者中为6/71。我们得出结论,超声心动图可识别出闭式二尖瓣交界分离术后预后较差的重度瓣下病变患者。然而,由于经济限制,在我们这样的发展中国家,该手术仍会被采用。

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