Teufelsbauer H, Prusa A M, Wolff K, Sahal M, Polterauer P, Lammer J, Hölzenbein T, Kretschmer G, Huk I
Department of Vascular Surgery, Research Institute of Interdisciplinary Clinical Vascular Medicine, University of Vienna-Medical School, Austria.
Eur J Vasc Endovasc Surg. 2003 Nov;26(5):494-500. doi: 10.1016/s1078-5884(03)00179-5.
to investigate whether appropriate selection in patients with infrarenal abdominal aortic aneurysms (AAA) for transfemoral endovascular aneurysm management (TEAM) or open graft replacement (OGR) may decrease in-hospital mortality rates (MR).
analysis of a clinical series over three periods in an university vascular center. Conclusions of the second period were drawn and prospectively applied in a third period and compared.
during the period 1989-1994 only OGR was available (n=170). In the interval 1995-2000 either OGR or TEAM were carried out (n=454). During the period 01/2001-07/2002 the conclusions concerning selection of treatment modality were drawn and prospectively applied in 132 consecutive patients. MR were recorded and possible significant differences were checked.
during the first period MR was 6.5%. Overall MR decreased to 3.7% in the second interval. Overall MR of the last period was improved to 1.5% (p<0.05). No patient died after OGR (0% vs 6.5%, p<0.04). As all patients with significant individual risk profiles were treated by TEAM, MR slightly increased (2.9%), but the difference remained insignificant (2.4% in period 2).
risk adjusted selection of treatment modality influences the results after OGR significantly, thereby reducing overall MR of elective AAA treatment.
研究对于肾下腹主动脉瘤(AAA)患者,经股动脉腔内动脉瘤治疗(TEAM)或开放移植置换术(OGR)的合理选择是否可降低住院死亡率(MR)。
对一所大学血管中心三个时期的临床系列进行分析。得出第二期的结论并前瞻性地应用于第三期并进行比较。
在1989 - 1994年期间仅可进行OGR(n = 170)。在1995 - 2000年期间,进行了OGR或TEAM(n = 454)。在2001年1月 - 2002年7月期间,得出关于治疗方式选择的结论并前瞻性地应用于132例连续患者。记录MR并检查可能存在的显著差异。
在第一期,MR为6.5%。在第二个时间段,总体MR降至3.7%。最后一期的总体MR改善至1.5%(p < 0.05)。OGR后无患者死亡(0%对6.5%,p < 0.04)。由于所有具有显著个体风险特征的患者均接受TEAM治疗,MR略有增加(2.9%),但差异仍不显著(第二期为2.4%)。
根据风险调整治疗方式的选择对OGR后的结果有显著影响,从而降低择期AAA治疗的总体MR。