碳水化合物吸收不良可能会增加婴儿的每日能量需求。

Carbohydrate malabsorption may increase daily energy requirements in infants.

作者信息

Valois Sandra, Rising Russell, Duro Debora, Cole Conrad, Cedillo Maribel, Lifshitz Fima

机构信息

EMTAC Inc., Miami, Florida 33134, USA.

出版信息

Nutrition. 2003 Oct;19(10):832-6. doi: 10.1016/s0899-9007(03)00160-6.

DOI:10.1016/s0899-9007(03)00160-6

PMID:14559316

Abstract

OBJECTIVE

Carbohydrate malabsorption in infants has been found to increase nutrient losses. However, the effect of this alteration on daily metabolic rate is unknown. We assessed daily metabolic rates in infants with asymptomatic carbohydrate malabsorption (ACM) after a single fruit juice load.

METHODS

Sixteen healthy infants with ACM (63.3 +/- 5.6 cm, 7.5 +/- 1.0 kg, 5.6 +/- 0.8 mo, peak breath hydrogen [BH2] = 39.1 +/- 22.4 ppm) and 16 without ACM (64.3 +/- 3.9 cm, 7.8 +/- 1.0 kg, 5.0 +/- 0.8 mo, BH2 = 9.4 +/- 4.7 ppm), after a single fruit juice load, had 24-h energy expenditure (24-h EE; kcal x kg(-1) x d(-1)), resting (RMR; kcal x kg(-1) x d(-1)) and sleeping (SMR; kcal x kg(-1) x d(-1)) metabolic rates extrapolated from 3.5-h assessments in the Enhanced Metabolic Testing Activity Chamber. Furthermore, RMR was calculated with the World Health Organization (WHO), Schofield weight-based and weight- and height-based equations. Carbohydrate absorption was determined by BH2. Differences (P < 0.05) were determined by t test.

RESULTS

All infants with ACM had greater (P < 0.05) extrapolated 24-h EE (91.2 +/- 24.8 versus 78.0 +/- 6.8) and RMR (71.8 +/- 15.2 versus 59.5 +/- 5.9). This represented an increase of 15-18.5%, respectively, in energy expenditures. Carbohydrate malabsorption was a significant determinant of EE, RMR, and SMR. However, the WHO (53.8 +/- 1.0 versus 54.1 +/- 0.9) and both Schofield equations (54.7 +/- 0.9 versus 54.9 +/- 1.0 and 50.6 +/- 7.5 versus 47.3 +/- 6.7) failed to detect any differences in RMR. There was a 20 percentile reduction in growth performance in infants with carbohydrate malabsorption.

CONCLUSIONS

Infants with ACM following fruit juice ingestion may have increased daily energy expenditure leading to increased metabolic requirements.

摘要

目的

已发现婴儿碳水化合物吸收不良会增加营养物质流失。然而，这种改变对每日代谢率的影响尚不清楚。我们评估了单次摄入果汁后无症状碳水化合物吸收不良（ACM）婴儿的每日代谢率。

方法

16名患有ACM的健康婴儿（身高63.3±5.6厘米，体重7.5±1.0千克，年龄5.6±0.8个月，呼气氢峰值[BH2]=39.1±22.4 ppm）和16名无ACM的婴儿（身高64.3±3.9厘米，体重7.8±1.0千克，年龄5.0±0.8个月，BH2=9.4±4.7 ppm），在单次摄入果汁后，通过在增强代谢测试活动室内进行3.5小时的评估推算出24小时能量消耗（24小时EE；千卡×千克⁻¹×天⁻¹）、静息代谢率（RMR；千卡×千克⁻¹×天⁻¹）和睡眠代谢率（SMR；千卡×千克⁻¹×天⁻¹）。此外，使用世界卫生组织（WHO）、基于Schofield体重以及基于体重和身高的公式计算RMR。通过BH2测定碳水化合物吸收情况。差异（P<0.05）通过t检验确定。

结果

所有患有ACM的婴儿推算出的24小时EE（91.2±24.8对78.0±6.8）和RMR（71.8±15.2对59.5±5.9）更高（P<0.05）。这分别代表能量消耗增加了15 - 18.5%。碳水化合物吸收不良是EE、RMR和SMR的重要决定因素。然而，WHO公式（53.8±1.0对54.1±0.9）以及两个Schofield公式（54.7±0.9对54.9±1.0和50.6±7.5对47.3±6.7）均未检测到RMR有任何差异。碳水化合物吸收不良的婴儿生长性能下降了20百分位数。