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通过磁心动图和直接胎儿心电图诊断胎儿房性心动过速。盐酸普萘洛尔治疗的病例报告。

Fetal atrial tachycardia diagnosed by magnetocardiography and direct fetal electrocardiography. A case report of treatment with propranolol hydrochloride.

作者信息

Ishii Keisuke, Chiba Yoshihide, Sasaki Yoshihito, Kawamata Kazuya, Miyashita Susumu

机构信息

Department of Perinatology, National Cardiovascular Center, Suita, Osaka, Japan.

出版信息

Fetal Diagn Ther. 2003 Nov-Dec;18(6):463-6. doi: 10.1159/000073144.

Abstract

At 26 weeks of gestation, fetal tachyarrhythmias (about 250 bpm) and ascites were detected by ultrasonography, and oral treatment with propranolol (30 mg/day) was commenced. Within 10 h, the fetal heart rate changed to approximately 85 bpm. The averaged fetal magnetocardiogram triggered by R peaks showed P wave and QRS complexes and an extra P wave. In addition, many extra nonconducted P-waves were detected in a fetal direct electrocardiogram. At 27 weeks of gestation, fetal tachycardia occurred again, and arrhythmia was diagnosed as the result of a blocked premature atrial contraction (PAC) with intermittent atrial tachycardia by fetal electrocardiogram. Administration of transplacental propranolol (90 mg/day) resolved the fetal tachyarrhythmias and ascites. Further studies are required to evaluate the efficacy and adverse effects of propranolol for fetal atrial tachycardia.

摘要

妊娠26周时,超声检查发现胎儿心动过速(约250次/分钟)和腹水,开始口服普萘洛尔治疗(30毫克/天)。10小时内,胎儿心率降至约85次/分钟。由R波触发的平均胎儿磁心动图显示有P波、QRS复合波及一个额外的P波。此外,在胎儿直接心电图中检测到许多额外的未下传P波。妊娠27周时,胎儿再次出现心动过速,胎儿心电图诊断心律失常为阻滞性房性早搏(PAC)伴间歇性房性心动过速。经胎盘给予普萘洛尔(90毫克/天)后,胎儿心动过速和腹水消失。需要进一步研究评估普萘洛尔治疗胎儿房性心动过速的疗效和不良反应。

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