[创伤后柯萨科夫综合征中脑生物电活动的特殊方面]

[Particular aspects of bioelectric brain activity in post-traumatic Korsakoff syndrome].

作者信息

Obraztsova E R, Sharova E V, Zaĭtsev O S, Voronov V G, Skoriatina I G

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2003;103(8):59-65.

Abstract

Thirty two patients, 21 with recurrent and 11 with chronic Korsakoff's syndrome of traumatic genesis, and 20 healthy subjects were studied, using visual and spectral coherent EEG analysis and investigation of three-dimensional localization of dipolar beta 1-activity sources (13-20 Hz EEG bands). In Korsakoff's syndrome, negative prognostic significance of a stable increase of EEG beta 1-activity coherence generated by a limited number of sources, preferably of frontal basal and stem localization, was found. In the context of clinical data, this EEG phenomenon may be related to inhibited state of corresponding cortical areas.

摘要

对32例患者（21例为创伤性复发性 Korsakoff 综合征，11例为慢性 Korsakoff 综合征）以及20名健康受试者进行了研究，采用视觉和频谱相干脑电图分析以及偶极子β1活动源（13 - 20 Hz脑电图频段）的三维定位研究。在 Korsakoff 综合征中，发现由有限数量的源（最好是额叶基底和脑干定位的源）产生的脑电图β1活动相干性稳定增加具有负面预后意义。结合临床数据来看，这种脑电图现象可能与相应皮质区域的抑制状态有关。