[副作用、不良药物相互作用及心脏毒性问题]
[Side effects, unwanted drug interactions and the problem of cardiotoxicity].
作者信息
Woroń Jarosław, Trabka-Janik Elzbieta, Kostka-Trabka Elzbieta
机构信息
Szpital Uniwersytecki 31-501 Kraków, ul. Kopernika.
出版信息
Przegl Lek. 2003;60(4):196-8.
PMID:14569882
Abstract
The problem of drug interactions is very important in pharmacotherapy. The interactions of some drugs (antihistamines, macrolides, fluoroquinolones, cisapride) with other can induce ventricular arrhythmias. A lot of non-antiarrhytmic drugs can prolong the QT interval, induce torsade de pointes and cardiotoxicity.
摘要
药物相互作用问题在药物治疗中非常重要。某些药物（抗组胺药、大环内酯类、氟喹诺酮类、西沙必利）与其他药物相互作用可诱发室性心律失常。许多非抗心律失常药物可延长QT间期，诱发尖端扭转型室速和心脏毒性。
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