皮肤沙粒样黑色素性神经鞘瘤：手术切除后无复发
Cutaneous psammomatous melanotic schwannoma: non-recurrence with surgical excision.
作者信息
Claessens Nadine, Heymans Olivier, Arrese Jorge E, Garcia Roy, Oelbrandt Bert, Piérard Gérald E
机构信息
Department of Dermatopathology, University Hospital Sart Tilman, Liège, Belgium.
出版信息
Am J Clin Dermatol. 2003;4(11):799-802. doi: 10.2165/00128071-200304110-00007.
BACKGROUND
Melanotic schwannoma is a pigmented nerve tumor that may be located in the skin and express local aggressivity. This tumor may occur singly. It may also be part of the Carney complex which consists of various, but specific, tumors.
OBJECTIVE
We report two cases of subcutaneous melanotic schwannoma localized on the trunk in two men aged 37 and 45 years.
METHODS
Conventional histology and immunohistochemistry were performed.
RESULTS
One melanotic schwannoma was associated with a cutaneous atypical myxoma and multiple melanocytic lesions, all being part of the Carney complex. The other case had no associated signs. In both cases, the melanotic schwannoma was completely excised and did not recur.
CONCLUSION
Melanotic schwannoma is rare and curable by surgery. It must not be confused with malignant melanoma and other pigmented neoplasms. The Carney complex should be carefully ruled out.
背景
黑色素性神经鞘瘤是一种色素性神经肿瘤，可位于皮肤并表现出局部侵袭性。该肿瘤可单发。它也可能是由多种特定肿瘤组成的卡尼综合征的一部分。
目的
我们报告两例发生于两名37岁和45岁男性躯干的皮下黑色素性神经鞘瘤病例。
方法
进行了常规组织学和免疫组织化学检查。
结果
一例黑色素性神经鞘瘤与皮肤非典型黏液瘤及多个黑素细胞病变相关，所有这些均为卡尼综合征的一部分。另一例无相关体征。两例中，黑色素性神经鞘瘤均被完全切除且未复发。
结论
黑色素性神经鞘瘤罕见，手术可治愈。它不应与恶性黑色素瘤及其他色素性肿瘤相混淆。应仔细排除卡尼综合征。
Zotero 插件