Lengerova Martina, Moore Richard C, Grant Sarah R, Vyskot Boris
Institute of Biophysics, Academy of Sciences of the Czech Republic, CZ-612 65 Brno, Czech Republic.
Genetics. 2003 Oct;165(2):935-8. doi: 10.1093/genetics/165.2.935.
Classical studies have established that, during meiosis, the X and Y chromosomes of the model dioecious plant Silene latifolia pair over a region at the ends of their q arms. We used fluorescence in situ hybridization of two molecular markers to demonstrate that this widely accepted model is incorrect. From these data we conclude that the homologous arm of the X chromosome is the p arm and that of the Y chromosome is the q arm. The establishment of the proper orientation of the pseudoautosomal region is essential for mapping and evolutionary studies.
经典研究已经证实,在减数分裂过程中,雌雄异株模式植物宽叶蝇子草的X和Y染色体在其q臂末端的一个区域配对。我们使用两种分子标记的荧光原位杂交来证明这个被广泛接受的模型是不正确的。从这些数据中我们得出结论,X染色体的同源臂是p臂,Y染色体的同源臂是q臂。假常染色体区域正确方向的确定对于图谱绘制和进化研究至关重要。