Pascual Samaniego M, González Fajardo J A, Fernández de la Gándara F, Calleja Escudero J, Sanz Lucas F J, Fernández Del Busto E
Servicio de Urología, Hospital Clínico Universitario, Valladolid.
Actas Urol Esp. 2003 Sep;27(8):640-4. doi: 10.1016/s0210-4806(03)72988-x.
Liposarcoma is a malignant tumor that has an embryologic origin from mesodermal tissue depending on fatty tissue. Although liposarcoma is only 0.1% of all human neoplasms, it is the most common histology subtype of retroperitoneal soft tissue sarcomas. This tumor grows slowly. Diffuse abdominal pain is its most frequent symptom and abdominal mass is the most common sign. Aggressive surgical treatment is basic to get a complete resection and a local disease control. This objective is difficult because of the large tumor size it gets in the retroperitoneal location and the multiorgan involvement that require the resection of a high percentage of contiguous organs. We report a case of a giant retroperitoneal liposarcoma presenting like continuous left hemiabdominal pain because of the visceral compression. The right kidney was involved and suffering from renal vessel enlargement without renal function. There is a high probability of microscopic residual disease and a good follow-up of the patients is necessary as well as an adjuvant radiation therapy in some cases.
脂肪肉瘤是一种起源于中胚层组织、依赖脂肪组织的恶性肿瘤。尽管脂肪肉瘤仅占所有人类肿瘤的0.1%,但它是腹膜后软组织肉瘤最常见的组织学亚型。这种肿瘤生长缓慢。弥漫性腹痛是其最常见的症状,腹部肿块是最常见的体征。积极的手术治疗是实现完整切除和局部疾病控制的基础。由于肿瘤在腹膜后位置生长较大且多器官受累,需要切除较高比例的相邻器官,因此实现这一目标很困难。我们报告一例巨大腹膜后脂肪肉瘤病例,因内脏受压表现为持续性左半腹疼痛。右肾受累,肾血管增粗但无肾功能。存在微小残留病灶的高可能性,因此对患者进行良好的随访以及在某些情况下进行辅助放疗是必要的。