Bose Bikash
Department of Neurosurgery, Christiana Care Health Care System, Christiana Hospital, 4755 Ogleton-Stanton Road, Newark, DE 19718, USA.
Spine J. 2002 Sep-Oct;2(5):381-5. doi: 10.1016/s1529-9430(02)00185-7.
Spinal sarcoidosis is rare. Most spinal sarcoid lesions are intramedullary, and only three cases of extramedullary sarcoid lesions have been reported.
To describe a case of an extramedullary sarcoid lesion in a patient that did not have systemic involvement and to review the literature of spinal sarcoidosis.
STUDY DESIGN/SETTING: Case report and review of the literature.
Case report.
Report of resolution of symptoms.
METHODS/DESCRIPTION: The patient was a 33-year-old woman who had neck pain and pain radiating to the right scapula area and down the right arm into her hand and wrist. She also complained of numbness, tingling, muscle spasms and tremors, and had difficulty with writing. Magnetic resonance imaging showed a mass that was extramedullary in the right lateral aspect of the spinal canal at the level of C5 and extending into the right C5-6 neuroforamen. Admitting diagnosis of neurofibroma was made. The patient underwent C4, C5 and C6 laminoplasty and gross total resection of an intradural extramedullary tumor. The lesion encroached on the neuroforamen on the right side involving the C6 nerve root, was grossly adherent to some of the rootlets and looked like a Schwannoma. Gross total resection of the tumor was performed. Pathological examination of the specimen showed a noncaseating granulomatosis consistent with sarcoid. Postoperative testing did not reveal systemic involvement of sarcoidosis. The patient was treated with corticosteroids.
The patient made a satisfactory recovery, returned to work full-time, and had no complaints of neurological symptoms.
An extramedullary sarcoid lesion is rare. Unlike intramedullary sarcoid lesions, it can be totally removed. If no systemic sarcoidosis is present, the patient can have a satisfactory recovery.
脊柱结节病较为罕见。大多数脊柱结节病病变位于髓内,仅有3例髓外结节病病变的报道。
描述1例无全身受累的患者发生髓外结节病病变的病例,并复习脊柱结节病的相关文献。
研究设计/研究背景:病例报告及文献复习。
病例报告。
症状缓解报告。
方法/描述:患者为一名33岁女性,有颈部疼痛,疼痛向右肩胛区放射,并沿右臂向下延伸至手部和腕部。她还主诉有麻木、刺痛、肌肉痉挛和震颤,并且书写困难。磁共振成像显示在C5水平椎管右侧有一髓外肿块,并延伸至右侧C5 - 6神经孔。入院诊断为神经纤维瘤。患者接受了C4、C5和C6椎板成形术及硬膜内髓外肿瘤的全切除。病变侵犯右侧神经孔,累及C6神经根,与一些神经根紧密粘连,外观类似神经鞘瘤。对肿瘤进行了全切除。标本的病理检查显示为与结节病相符的非干酪样肉芽肿。术后检查未发现结节病的全身受累情况。患者接受了皮质类固醇治疗。
患者恢复良好,全职返回工作岗位,无神经症状主诉。
髓外结节病病变罕见。与髓内结节病病变不同,它可以完全切除。如果不存在全身结节病,患者可获得满意的恢复。